Standardization of Botanicals, Vol. 1

About Book

ISBN 9788190646758
Presentation Hardbound, 304 Pages
Edition 2nd Edition 2011
Weight 0.75 Kg
Author DPS Kohli,Dr. V. Rajpal
Price USD 100
Availability In Stock

There has been a resurgence in usage of herbal medicine in the past few years, not only among the traditional medicine users (ethno-medicine) but also among the modern consumers of herbal products. This is supplemented with all round growth of similar natural products among the nutritional supplements and personal care segments. The question of quality therefore acquires greater importance today than ever before.

While there are some books available on identification, description, pharmacological action, safety aspects etc. of medicinal herbs, very few books can be found on quantitative testing of medicinal herbs. This book fulfills that gap in knowledge base with detailed, ready to use and validated methods of analysis to be perfomed in a quality control laboratory. This book will be welcomed by all those who are concerned about the standardization of botanicals as it provides analytical procedures for extracts as well as phytochemicals.

This book is an attempt to provide, not only the quantitative testing methods but also chemical constituents, extraction processes, specifications of various extracts, therapeutic functions, dosage, pharmacological properties, toxicity/safety aspects and references. Volume I of this book contains 25 widely used medicinal herbs.

ABOUT THE AUTHOR

Dr. Rajpal obtained his doctorate in phytochemistry in 1976 and since then has been associated with the herb processing and testing of botanicals, their extracts and phytochemicals in an industrial setting. He also provides consultancy services to various companies in this sector. He is presently working as a Technical Director with a company engaged in extraction of botanicals.

WHO SHOULD BUY THIS BOOK

  • Manufacturers of herbal extracts
  • Manufacturers of herbal formulations
  • Manufacturers of herbal cosmetics
  • Manufacturers of nutritional supplements
  • Testing laboratories
  • Research Institutions
  • Herb growers
  • Academic institutions
  • Regulatory affairs specialists

CONTENTS

Preface

Acorus calamus

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Alternate Extraction Process

Specifications Sheet -

   Dry Extract-Powder (10:1)

Estimation of ß - asarone in Acorus calamus

   Dry Extract by HPTLC

Pharmacological and Biological Activities

Therapeutic Indications

Dosage

Toxicity and Safety Aspects

References

 

Aloe barbadensis

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Extraction process of Aloe Gel and Powder

Specifications Sheet-

(1) Gum Dry Extract

(2) Leaf Dry Extract

(3) Gel - stablised

Assay (For Hydroxy Anthracene Derivatives)

Assay (Mucilage - Mucopolysaccharides)

Determination of Aloesin in Aloe Extract and Aloe Preparations by HPLC

Pharmacological and Biological Activities

Therapeutic Indications

Shelf-Life

Uses

Dosage

Toxicity and Safety Aspects

Reference

 

Andrographis paniculata

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Dry Extract (Spray dried Powder)

(2) Soft Extract

(3) Andrographolide

Estimation of Total Bitters as

   Andrographolides in Andrographis

   Paniculata plant (Kalmegh) Extract

Estimation of Andrographolides by Spectrophotometric Method

HPLC Analysis of Andrographolide

Pharmacological and Biological Activities

Clinical Research

Therapeutic Indications

Dosage

Contra-indications / Cautions

Official Pharmacopoeial Preparations

References

 

Bacopa monnieri

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet - Herb Dry Extract

Estimation of Total Saponins as

   Bacosides A & B in Bacopa monnieri

   Dry Extract

HPLC Analysis of Bacosides A & B

Quantitative Determination of

   Bacosides by HPTLC

Determination of Total Bacosides as Bacoside A by UV Spectroscopy

Pharmacological and Biological Activities

Clinical Research

Therapeutic Indications

Dosage

References

 

Boswellia serrata

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Isolation of ß- Boswellic Acid

Conversion of ß-Boswellic Acid acetate to

   ß - Boswellic Acid

Specifications Sheet - Gum Dry Extract -  Vacuum Dried Powder

Method of Estimation of Boswellic Acid by Non-Aqueous Titration in Boswellia serrata (Sallaki) Dry Extract

Pharmacological and Biological Activities

Therapeutic Functions

Dosage

References

 

Cassia angustifolia

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

   (1) Cassia angustifolia Leaf Dry Extract

   (2) Sennosides - 30% To 60%

Assay of Sennosides (USP-XXIV, P. 1517)

Pharmacological and Biological Activities

Toxicity and Safety Data

Dosage

Therapeutic Indications

Contra-indications

References

 

Centella asiatica

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

   Dry Extract (Vacuum Dried Powder)

Estimation of Sapogenins as Asiatic Acid

Assay by HPLC Procedure

Estimation of Saponin by Gravimetric Method

Pharmacological and Biological Activities

Clinical Research

Official Pharmacopoeial Preparations

Therapeutic Indications

Dosage

Contra-Indication / Cautions / Warning

References

 

Cissus quadrangularis

Syn. Vitis quadrangularis (Heliotropium indicum)

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet - Stem Dry Extract

Quantitative Testing

Pharmacological and Biological Activities

Clinical Research

Therapeutic Indications

Dosage

References

 

Commiphora mukul Gum (Guggul Gum)

 

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Guggul gum Soft Extract

(2) Guggul gum Dry Extract Powder 10:1

(3) Guggul gum Dry Extract Powder 5:1

Estimation of Guggulsterones by Spectrophotometer

Estimation of Lipids in Guggul Extract

UV Spectrum Profile

Pharmacological and Biological Activities

Side Effects

Clinical Research

Therapeutic Functions

Dosage

References

 

Eclipta alba

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Herb Dry Extract

(2) Herb Soft Extract

Estimation of Bitters

Pharmacological and Biological Activities

Clinical Research

Therapeutic Indications

Dosage

Safety Aspects

References

 

Garcinia cambogia

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Manufacturing Process

Specifications Sheet - Dry Extract - Spray dried powder

Quantitative Estimation of (-) Hydroxy Citric Acid in Garcinia cambogia Extract

Estimation of (-) Hydroxy Citric Acid by HPLC

Pharmacological and Biological Activities

Clinical Research

Therapeutic Indications

Dosage

References

 

Glycyrrhiza glabra

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process for Thick Paste/Powder

Manufacturing Process - of Mono-ammonium Gylcyrrhizinate and Deglycyrrhizinised Liquorice Extract

Specifications Sheet -

(1) Root Dry Extract

(2) Root Thick Paste

(3) De-Glycyrrhizinated Liquorice Dry Extract

(4) Mono Ammonium Glycyrrhizinate

(5) Sodium Glycyrrhizinate

(6) Glycyrrhizic Acid

(7) Glycyrrhitinic Acid

Estimation of Flavonoids in Glycyrrhiza glabra Dry Extract and De-Glycyrrhizinised Liquorice Extract

Estimation of Crude Glycyrrhizin by Gravimetric Method (Garret Method)

Estimation of Glycyrrhizin by Spectrophotometric Method

Estimation of Glycyrrhizic Acid by HPTLC

Estimation of Glycyrrhizin by TLC - Densitometry

Testing method of Mono-ammonium Glycyrrhizinate

Manufacturing Process of Sodium Glycyrrhizinate

Conversion of Mono Ammonium Glycyrrhizinate to Glycyrrhitinic Acid

Conversion of Glycyrrhitinic Acid to Its Acetate

Conversion of Glycyrrhitinic Acid to Its Succinate Derivative (Carbenoxolone)

Process Flow Chart For Mono Ammonium Glycyrrhizinate [MAG]

Process Flow Chart For De-Glycyrrhizinated Liquorice Extract [DGL]

Pharmacological and Biological Activities

Clinical Research

Side effects

Therapeutic Indications

Dosage

References

 

Gymnema sylvestre

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Leaf Dry Extract

(2) Leaf Purified Dry Extract

Estimation of Crude Gymnemic Acid from Gymnema sylvestre Leaf Extract

Quantitative assay method for Total Gymnemasaponin by High Performance Liquid Chromatography (HPLC)

An alternate HPLC procedure for estimating Gymnemic Acid

Pharmacological and Biological Activities

Clinical Research

Therapeutic Indications

Dosage

References

 

Hypericum perforatum

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Dry Extract Powder

(2) Soft Extract

Estimation of Dianthrones calculated as Total Hypericin

Therapeutic Indications

Dosage

Pharmacological and Biological Activities

Clinical Research

Toxicity and Safety Data

References

 

Mucuna pruriens

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Manufacturing Process of L - Dopa

Specifications Sheet - Processed Mucuna Seeds Dry Powder

Estimation of L-Dopa in Mucuna pruriens Extract

Pharmacological and Biological Activities

Clinical Research

Therapeutic Indications

Dosage

References

 

Passiflora incarnata

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Soft Extract

(2) Dry Extract

Estimation of Flavonoids by HPLC

Pharmacological and Biological Activities

Therapeutic Indications

Dosage

Toxicity and safety data

References

 

Phyllanthus amarus

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Soft Extract (Thick Paste)

(2) Herb Dry Extract

Estimation of Phyllanthin and Hypophyllanthin by HPLC

Thin Layer Chromatographic Analysis of Phyllanthus Species

Estimation of Bitters as Lignan

Pharmacological and Biological Activities

Therapeutic Functions

Dosage

References

 

Picrorhiza kurroa

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Thick Paste

(2) Dry Extract

TLC Procedure of Picrorhiza kurroa

Estimation of Bitters as Kutkin In Picrorhiza kurroa Root (Kutki) Extract

HPLC Procedure

Pharmacological and Biological Activities

Clinical Research

Therapeutic Functions

Dosage

References

 

Polygala senega

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Soft Extract (Polygala chinensis) (Senega Indian)

(2) Dry Extract Polygala chinensis (Senega Indian)

Estimation of Total Triterpenic Saponins in Senega Root / Extract

Pharmacological and Biological Activities

Therapeutic Functions

Dosage

Toxicity and Safety Aspects

References

 

Tinospora cordifolia

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet - Dry Extract

Estimation of Bitters in Tinospora cordifolia Extract

Estimation of Cordifolioside 'A' by HPLC Method

HPTLC Analysis

Pharmacological and Biological Activities

Clinical Research

Therapeutic Functions

Dosage

References

 

Tribulus terrestris

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Processed Tribulus terrestris Dry Extract

(2) Tribulus terrestris Dry Extract

Estimation of Total Saponins in Tribulus terrestris (Gokhru) Extract

TLC Analysis

Pharmacological and Biological Activities

Therapeutic Functions

Dosage

References

 

Trigonella foenumgraecum

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Dry Extract

(2) Soft Extract

Testing Procedure For Saponins in Trigonella foenumgraecum (Methi Dana) Extract

Pharmacological and Biological Activities

Therapeutic Indications

Dosage

Uses and Applications

References

 

Valeriana wallichii

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet -

(1) Thick Paste

(2) Dry Extract

Quantitative Estimation of Valepotriates

Valerenic Acid Determination by HPLC

Pharmacological and Biological Activities

Clinical Research

Therapeutic Indications

Dosage

Toxicity and Safety Aspects

References

 

Withania somnifera

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process

Specifications Sheet - Dry Extract

Estimation of Withanolides

Estimation of Glycowithanolides

Estimation of Total Alkaloids

Pharmacological and Biological Activities

Contraindications / Cautions

Therapeutic Indications

Dosage

References

 

Zingiber officinale

Distribution and Description of the Plant

Chemical Constituents of the Herb

Extraction Process for thick paste

Extraction Process for dry extract

Specifications Sheet -

(1) Thick Paste

(2) Dry Extract

Analysis Procedure

Pharmacological and Biological Activities

Clinical Research

Therapeutic Functions

Dosage

Toxicity and Safety Data

References

 

ANNEXURES

Annexure - 1 Herb Extraction Chart

Annexure - 2 Websites on Herbal Medicines

Index of Chemical Constituents


New User?

Bookseller?